People requiring treatment for severe acne can expect their doctors
to ask about their mental health before and during any treatment with the acne
medication isotretinoin (e.g. Roaccutane, Accutane, Oratane).
While it is one of the most effective treatments for severe acne, isotretinoin
use has been linked to possible side effects such as depression and suicidal thoughts
or behavior in some people. However research has struggled to tease out the contribution of mood
changes caused by living with severe acne itself - irrespective of the type of
A recent UK report about isotretinoin, endorsed by Australia’s
Therapeutic Goods Administration (TGA), has reiterated the advice that acne can
be associated with mental health disorders, regardless of whether or not
isotretinoin treatment is used.
The UK report also emphasised that because of its potential for
severe side effects, isotretinoin should only be prescribed for people with
severe cystic acne who have not responded to other treatment options.
Melbourne dermatologist and All About Acne spokesperson Dr Mei Tam
said isotretinoin was a very effective acne treatment.
“We have had years of experience with isotretinoin now and most
people can use it safely and expect good results. The most common side effects
such as dry, sensitive and irritated skin can be alleviated by the use of
“One of the other potential problems is that acne can initially flare
up with isotretinoin use and look worse before it gets better. That can be very
distressing for young people who are desperate for clear skin,” she said.
Dr Tam said Australian doctors were well aware of the importance of
screening and monitoring acne patients for mental health issues but family and
friends can play a role too.
“We know that physical scars aren’t the only consequence of severe
acne. Acne can erode people’s self
esteem and contribute to depressed mood so it’s really important to ask how
someone is feeling and to raise any concerns they have about mental health.”
For more information on isotretinoin, talk to a doctor or pharmacist
or read the Consumer Medicine Information (CMI) about the prescribed medicine.